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Vol. 22 (2019 year), No. 3, DOI: 10.21443/1560-9278-2019-22-3

Pozdnyakova O. G., Belavina G. A., Avstrievskih A. N., Poznyakovsky V. M.
Biologically active plant-based complex: Production technology, quality indicators, functional properties

Biologically active complex on plant materials is part of a specialized product which due to some antioxidant properties helps to slow down the occurrence of age-related changes in the body. The technology of this specialized product in the encapsulated form of a biologically active additive (BAA) has been developed. The main stages of production include: preparation of raw materials and examination of accompanying documents, weighing and dosing of raw materials; sieving, grinding and resieving; mixing and quality control; encapsulation and dusting; packaging, labeling and storage. The hygienic safety of the product has been proved by examining microbiological indicators – yeast and mold, E. Coli, KMAFАnM, pathogenic microorganisms, including salmonella, coliforms (BHCP), toxic metals, pesticide. The content of toxic metals and pesticides has been studied. All indicators are within the requirements of the current regulatory documents. Sparing modes of production parameters, storage at the temperature not exceeding 25 °C and a slight moisture content in the product (3–5 %) guarantee the stability of the biologically active components of the formulation and high consumer properties. Regulated quality indicators are established, including nutritional value in 1 capsule, mg: ascorbic acid content – 30; vitamin E – 10; beta-carotene – 2. The inclusion in the diet of two capsules (recommended daily amount) guarantees the intake, mg: vitamin C (ascorbic acid) – 60 (67); vitamin E – 20 (67); beta carotene – 4 (80). In brackets – % of daily need. The functional orientation of dietary supplements based on the pharmacological characteristics of the prescription ingredients has been considered. The product is positioned as a specialized antioxidant complex to protect the body from the effects of free radicals and increase the functional activity of the immune system. The effectiveness of dietary supplements is based on the synergistic properties of biologically active substances of the peach leaf extract.

(in Russian, стр.6, fig. 1, tables. 3, ref 9, AdobePDF, AdobePDF 0 Kb)

Vol. 25 (2022 year), No. 3, DOI: 10.21443/1560-9278-2022-25-3

Poznyakovsky V. M. , Zakharenko M. A. , Avstrievsikh A. N. , Zinovieva E. N.
Specialized product in the form of a biotechnological complex of bacterial metafiltrates for selective sorption of endotoxins and metabolic correction of intestinal microflora

The intestinal microflora of the human body performs vital regulatory functions. In the course of the study, a biotechnological complex has been developed in the form of dietary supplements, the functional properties of which are aimed at regulating the intestinal biocenosis, inhibiting pathogenic and conditionally pathogenic microflora, as well as developing a useful part of the microbiota. The qualitative and quantitative composition of the specialized product includes, mg/5.5 g, floration (soluble dietary fiber) – 1,375 (1,238); metafiltrates Bifidobacterium bifidum – 620, Bifidobacterium breve – 600, Lactobacillus delbrueckii – 500, Hericium coralloides – 242.5, Propionibacterium freudenreichii – 100; lactulose (50 %) – 400; postbiotic metafiltrate Subtizym – 200; silicon dioxide – 30; endofulvin (Endofulvin, humic acids) – 9.62 (7.5); chitosan – 5; para-aminobenzoic acid – 2; nicotinamide (vitamin B₃) – 1.81 (1.8); cysteine – 1.25; calcium pantothenate (vitamin B₅) – 0.654 (0.6); riboflavin (vitamin B₂) – 0.16. An innovative feature of the production technology is a liquid concentrated form of dietary supplements, which ensures rapid passage through the stomach, the preservation of active principles and the effectiveness of the implementation of specified functional properties. The organoleptic, microbiological and physicochemical indicators of quality and safety have been studied, the results of which make it possible to determine the regulated characteristics and shelf life – 1 year at the temperature of 0–25 °C, relative humidity of not more than 60 %. The developed complex is recommended for use in the amount of 5.5 g of concentrate 3 times a day; course duration – 1 month. The product has passed production tests at ArtLife LLC (Tomsk).

(in Russian, стр.9, fig. 0, tables. 9, ref 12, AdobePDF, AdobePDF 0 Kb)